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Table 1 Covariate effects on EC50 values

From: Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe

Adjusted EC50 value Estimated EC50 in ng/mg of atazanavir in hair
(95% Confidence Interval)
p-value
EC50: Base model 4.5 (3.5–7.6) (NA -reference model)
EC50: Follow-up event 3.3 (1.4 - □) < 0.001
EC50: 100% Self-reported adherence 4.5 (3.5–7.6) 0.304
EC50: 50% Self-reported adherence 4.5 (1.8 – □) 0.304
EC50: Normal BMI-for-age participants 3.8 (2.7–6.8) 0.927
EC50: Overweight participants 3.5 (1.8–7.5) 0.927
EC50: Underweight participants 5.5 (3.5 – □) 0.927
EC50: Mature care-givers 3.8 (2.3–6.4) 0.636
EC50: Full model 2.4 (□ – 5.5) 0.919