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Table 1 Demographic, baseline, and morphometric characteristics of participants

From: Effect of perioperative use of parecoxib on chronic post-surgical pain in elderly patients after hepatectomy: a prospective randomized controlled study

Factor

Parecoxib Group

(N = 51)

Placebo Group

(N = 54)

P value

Demographic and baseline

 Age, y

69.9 ± 3.9

70.1 ± 4.2

0.79

 Male, No. (%)

41 (80.4)

38 (70.4)

0.23

 BMI, kg/m2

23.6 ± 2.7

23.0 ± 3.1

0.33

 ASA status, No. (%)

  

0.66

  I

22 (43.1)

21 (38.9)

 

  II

29 (56.9)

33 (61.1)

 

 History of diabetes, No. (%)

3 (5.9)

10 (18.5)

0.05

 History of hypertension, No. (%)

24 (47.1)

26 (48.1)

0.91

 HADS- anxiety score, point

2.2 ± 1.7

2.7 ± 2.7

0.73

 HADS- depression score, point

1.4 ± 1.4

1.0 ± 1.8

0.03a

Surgical characteristics

 TNM stage of hepatocellular carcinoma

  

0.399

  T1N0M0

18 (35.3)

13 (24.1)

 

  T2N0M0

22 (43.1)

25 (46.3)

 

  T3N0M0

11 (21.6)

16 (29.6)

 

 Duration of surgery, h

2.5 ± 0.9

2.4 ± 1.1

0.43

 Segment resected, No. (%)

  

0.07

  1

25 (49.0)

25 (46.3)

 

  2

18 (35.3)

11 (20.4)

 

  3

8 (15.7)

18 (33.3)

 

 Pringle manerver duration, min

19.7 ± 12.4

18.9 ± 11.9

0.74

 Intraoperative blood loss, mL

245.5 ± 188.8

229.1 ± 182.2

0.65

 Intraoperative urine output, mL

277.5 ± 254.4

267.0 ± 233.9

0.83

 Fluids volume (crystalloids, colloids), L

2.1 ± 0.6

1.9 ± 0.6

0.18

 Intraoperative fentanyl infusion, ug/kg

3.7 ± 0.7

3.6 ± 0.7

0.44

  1. Data are reported as No. (%) or means ± SD as appropriate
  2. ASA American Society of Anesthesiologists; BMI body mass index; HADS Hospital Anxiety and Depression Scale
  3. a Patients in the parecoxib group have significantly different depression scores from those in the placebo group (P = 0.03), but the clinical significance was inapparent. Because the cutoff of the depression score in HADS was 8 points, the depression status between-group was similar