Fig. 5
Results of peritoneal CFU assessment to determine the efficacy of melittin along with untreated and colistin/vancomycin controls. The neutropenic mice (n = 15 each group) were inoculated with a sub-lethal amount of A. baumannii (A-106 CFU/mouse), S. aureus (B-106 CFU/mouse), and K. pneumonia (C-107 CFU/mouse) and treated with phosphate buffered saline (PBS), melittin (2.4 mg/kg) and colistin/vancomycin as described in methods. Results are expressed as mean ± SD. (n = 5 each studied time point). Difference were defined as significant as *p < 0.5, **p < 0.01, and ***p < 0.001 between groups