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Table 9 e-Values

From: Causal inference multiple imputation investigation of the impact of cannabinoids and other substances on ethnic differentials in US testicular cancer incidence

Parameter

Estimate (C.I.)

R.R. (C.I.)

E-Values

LINEAR MODELS

 lm(TC_Rate ~ EthnTHCExp * Race)

  Ethnic_THC_Exposure

0.06 (0.04, 0.08)

1.31 (1.18, 1.45)

1.95, 1.66

In Ethnic Dataset, Long

  (lm(Rate ~ Race)

  Cannabis

0.47 (0.41, 0.52)

2.04 (1.68, 2.47)

3.05, 2.76

 lm(Rate ~ Time * mrjmon)

  Cannabis

0.49 (0.44, 0.55)

2.19 (1.95, 2.32)

3.68, 3.31

MIXED EFFECTS MODELS

 lme(TestCa ~ Ethnic_THC_Exposure)

  Ethnic_THC_Exp

0.05 (0.04, 0.06)

1.23 (1.19, 1.28)

1.78, 1.68

 lme(TestCa ~ Race + Ethnic_THC_Exposure)

  Ethnic_THC_Exp

0.24 (0.15, 0.32)

1.21 (1.13, 1.30)

1.72, 1.50

 lme(TestCa ~ Race * Ethnic_THC_Exposure)

  Hispanic-Am.: Ethnic_THC_Exp

0.58 (0.4, 0.77)

1.67 (1.27, 2.26)

2.74, 1.85

 lme(TestCa ~ Year * Ethnic_THC_Exposure)

  Ethnic_THC_Exp

1.39 (1.25, 1.53)

1.82 (1.72, 1.93)

3.05, 2.83

 Additive Model - Drugs

  Ethnic_THC_Exp

0.05 (0.04, 0.06)

1.29 (1.23, 1.34)

1.89, 1.77

 Interactive Model - 3-Way

  Cigarettes: Ethnic_THC_Exp

0.44 (0.31, 0.57)

949 (4.86, 18.54)

18.8, 9.20

 Interactive Model - 4-Way

  Ethnic_THC_Exp: Analgesics

0.22 (0.07, 0.37)

3.14 (1.45, 6.79)

5.74, 2.28

  Ethnic_THC_Exp

0.64 (0.17, 1.1)

26.50 (2.44, 287.17)

52.52, 4.33

IV-REGRESSION

 ivreg(TestCa ~ Ethnic_THC_Exposure)

  Ethnic_THC_Exposure

1.03 (0.89, 1.17)

1.07 (1.06, 1.07)

1.33, 1.30

 ivreg(TestCa ~ Ethnic_THC_Exposure)

  Ethnic_THC_Exposure

0.89 (0.88, 0.91)

  

 ivreg(TestCaRt ~ log(EthnTHCExp): Race)

  Ethnic_THC_Exp: Asian-Am.

2.72 (0.84, 4.61)

1.21 (1.06, 1.38)

1.72, 1.31

  Ethnic_THC_Exp: NHCaucasian-Am.

0.44 (0.3, 0.59)

1.03 (1.02, 1.04)

1.21, 1.17

 ivreg(TestCa ~ Ethnic_THC_Exp * Race)

  NHCaucasian-Am.: Ethnic_THC_Exp

1.22 (1.16, 1.27)

1.01 (1.01, 1.02)

1.12, 1.12

  Hispanic-Am.: Ethnic_THC_Exp

1.48 (1.38, 1.59)

1.01 (1.01, 1.02)

1.14, 1.13

 ivreg(Rate ~ Cigarettes * AUD + Analgesics + Cocaine + MHY + * Ethnic_THC_Exposure)

  Ethnic_THC_Exp

0.32 (0.2, 0.43)

1.04 (1.03, 1.06)

1.25, 1.19

 ivreg(Rate ~ Ethn_THC_Exposure + Race)

  Ethn_THC_ExposureNHCaucasian-Am._THC_Exposure

0.08 (0.02, 0.13)

1.01 (1.00, 1.01)

1.10, 1.05

 ivreg(TestCa ~ Cigarettes * AUD * Cannabis + + Cocaine + MHY + Analgesics)

  AUD: Ethnic_THC_Exp

312.53 (290.54, 334.53)

1.22E+ 05 (5.36E+ 04, 2.77E+ 05)

2.43E+ 05, 1.07E+ 05

  Cigarettes: Ethnic_THC_Exp

150.41 (139.67, 161.15)

280.39 (187.63, 419.03)

560.29, 374.76

 ivreg(TestCa ~ Cigarettes * AUD * Ethnic_THC_Exp * + Cocaine + MHY + Analgesics)

  Ethnic_THC_Exp

0.55 (0.05, 1.05)

1.03 (1.00, 1.06)

1.21, 1.06

MULTIPLE IMPUTATION

 Ethnic_THC_Exposure Alone

  Ethnic_THC_Exposure

0.68 (0.62, 0.74)

1.44 (1.39, 1.49)

2.35, 2.13

 Ethnic_THC_Exposure * Race

  Ethnic_THC_Exposure

0.19 (0.14, 0.24)

1.24 (1.17, 1.30)

1.77, 1.62

 Additive - Drugs

  Ethnic_THC_Exposure

0.72 (0.66, 0.79)

1.48 (1.43, 1.53)

2.31, 2.20

 Interactive Full Model

  Ethnic_THC_Exposure

0.12 (0.07, 0.18)

1.14 (1.08, 1.22)

1.56, 1.37

 Quintiles

  Quintile 5

0.29 (0.06, 0.51)

1.15 (1.03, 1.28)

1.57, 1.21

 Dichotomized Quintiles

  Upper_2_Quintiles

0.2 (0.06, 0.35)

1.10 (1.03, 1.18)

1.44, 1.21

LEGAL STATUS

 Whites

  Liberal

0.09 (0.06, 0.12)

1.57 (1.36, 1.81)

2.51, 2.07

 Blacks

 Liberal

0.22 (0.12, 0.32)

2.83 (1.78, 4.84)

5.10, 2.96

 Both_Races

  Medical

0.62 (0.43, 0.8)

1.79 (1.51, 2.13)

2.99, 2.39

  Decriminalized

0.33 (0.15, 0.51)

1.36 (1.15, 1.62)

2.07, 1.56

  Legal

0.61 (0.24, 0.98)

1.78 (1.25, 2.55)

2.97, 1.82

 Dichotomized_Status

  Liberal

0.48 (0.34, 0.62)

1.58 (1.38, 1.81)

2.54, 2.11

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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