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Table 2 Comparison of secondary structure using RAMPAGE server between AKT1and W80R mutants

From: Simulation studies, 3D QSAR and molecular docking on a point mutation of protein kinase B with flavonoids targeting ovarian Cancer

S.No

Protein Properties

AKT1(wild)

W80R(mutant)

1

Total amino acids

480

480

2

Number of residues in favoured region (−98.0% expected)

388 (81.2%)

379 (79.3%)

 

Number of residues in allowed region(−2.0% expected)

61 (12.8%)

66 (13.8%)

3

Number of residues in outlier region

29 (6.1%)

33 (6.9%)