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Table 6 Comparison of the number of reports for each factor before and after propensity score matching

From: Pharmacovigilance study of anti-infective-related acute kidney injury using the Japanese adverse drug event report database

 

before propensity score matching 

after propensity score matching  

≥ 2 drugs (n = 9,711)

1 drug (n = 29,938)

p

Standard mean difference

≥ 2 drugs (n = 6,044)

1 drug (n = 6,044)

p

Standard mean difference

Sex

  

< 0.0001*

0.0985

  

0.5788

0.0100

 Male

5683 (0.5861)

16037 (0.5373)

  

3561 (0.5892)

3591 (0.5941)

  

 Female

4014 (0.4139)

13809 (0.4627)

  

2483 (0.4108)

2453 (0.4059)

  

Age (year)

  

< 0.0001*

   

0.9991

 

 < 10

669 (0.0693)

1671 (0.0563)

  

358 (0.0592)

363 (0.0601)

  

 10

462 (0.0479)

1183 (0.0399)

  

285 (0.0472)

265 (0.0438)

  

 20

477 (0.0494)

1586 (0.0534)

  

238 (0.0394)

225 (0.0372)

  

 30

599 (0.0621)

2367 (0.0797)

  

344 (0.0569)

341 (0.0564)

  

 40

723 (0.0749)

2186 (0.0736)

  

455 (0.0753)

448 (0.0741)

  

 50

1256 (0.1302)

3506 (0.1181)

  

812 (0.1343)

819 (0.1355)

  

 60

2095 (0.2171)

5787 (0.1949)

  

1382 (0.2287)

1399 (0.2315)

  

 70

2195 (0.2275)

6903 (0.2325)

  

1476 (0.2442)

1485 (0.2457)

  

 80

1047 (0.1085)

3821 (0.1287)

  

636 (0.1052)

643 (0.1064)

  

 90

122 (0.0126)

669 (0.0225)

  

57 (0.0094)

55 (0.0091)

  

 100

3 (0.0003)

7 (0.0002)

  

1 (0.0002)

1 (0.0002)

  

Height (cm)

  

< 0.0001*

   

0.9998

 

 < 10

0 (0.0000)

0 (0.0000)

  

0 (0.0000)

0 (0.0000)

  

 10

0 (0.0000)

1 (0.0001)

  

0 (0.0000)

0 (0.0000)

  

 20

3 (0.0005)

1 (0.0001)

  

2 (0.0003)

1 (0.0002)

  

 30

31 (0.0050)

19 (0.0010)

  

15 (0.0025)

15 (0.0025)

  

 40

22 (0.0035)

44 (0.0024)

  

20 (0.0033)

21 (0.0035)

  

 50

21 (0.0034)

44 (0.0024)

  

20 (0.0033)

26 (0.0043)

  

 60

29 (0.0047)

62 (0.0033)

  

28 (0.0046)

27 (0.0045)

  

 70

52 (0.0084)

111 (0.0060)

  

48 (0.0079)

47 (0.0078)

  

 80

46 (0.0074)

85 (0.0046)

  

43 (0.0071)

45 (0.0074)

  

 90

53 (0.0085)

88 (0.0047)

  

49 (0.0081)

51 (0.0084)

  

 100

42 (0.0068)

98 (0.0053)

  

40 (0.0066)

41 (0.0068)

  

 110

42 (0.0068)

114 (0.0061)

  

42 (0.0069)

39 (0.0065)

  

 120

58 (0.0093)

132 (0.0071)

  

58 (0.0096)

62 (0.0103)

  

 130

102 (0.0164)

403 (0.0217)

  

99 (0.0164)

88 (0.0146)

  

 140

747 (0.1202)

2449 (0.1319)

  

727 (0.1203)

723 (0.1196)

  

 150

1889 (0.3038)

5975 (0.3218)

  

1847 (0.3056)

1824 (0.3018)

  

 160

2108 (0.3391)

6222 (0.3351)

  

2058 (0.3405)

2084 (0.3448)

  

 170

890 (0.1432)

2477 (0.1334)

  

868 (0.1436)

871 (0.1441)

  

 180

81 (0.0130)

238 (0.0128)

  

79 (0.0131)

79 (0.0131)

  

 190

1 (0.0002)

4 (0.0002)

  

1 (0.0002)

0 (0.0000)

  

 ≥ 200

0 (0.0000)

0 (0.0000)

  

0 (0.0000)

0 (0.0000)

  

Weight (kg)

  

0.0003*

   

0.9916

 

 < 10

200 (0.0264)

369 (0.0177)

  

117 (0.0194)

120 (0.0199)

  

 10

264 (0.0348)

620 (0.0298)

  

162 (0.0268)

165 (0.0273)

  

 20

190 (0.0250)

470 (0.0226)

  

119 (0.0197)

113 (0.0187)

  

 30

597 (0.0787)

1683 (0.0808)

  

437 (0.0723)

438 (0.0725)

  

 40

1813 (0.2390)

4929 (0.2366)

  

1498 (0.2478)

1492 (0.2469)

  

 50

2213 (0.2917)

6176 (0.2964)

  

1844 (0.3051)

1851 (0.3063)

  

 60

1506 (0.1985)

4135 (0.1985)

  

1204 (0.1992)

1212 (0.2005)

  

 70

559 (0.0737)

1672 (0.0802)

  

457 (0.0756)

465 (0.0769)

  

 80

156 (0.0206)

503 (0.0241)

  

132 (0.0218)

131 (0.0217)

  

 90

47 (0.0062)

157 (0.0075)

  

44 (0.0073)

32 (0.0053)

  

 100

15 (0.0020)

62 (0.0030)

  

9 (0.0015)

10 (0.0017)

  

 110

12 (0.0016)

19 (0.0009)

  

10 (0.0017)

6 (0.0010)

  

 120

4 (0.0005)

7 (0.0003)

  

1 (0.0002)

0 (0.0000)

  

 130

0 (0.0000)

3 (0.0001)

  

0 (0.0000)

0 (0.0000)

  

 140

4 (0.0005)

3 (0.0001)

  

3 (0.0005)

2 (0.0003)

  

 150

3 (0.0004)

11 (0.0005)

  

3 (0.0005)

3 (0.0005)

  

 160

3 (0.0004)

7 (0.0003)

  

3 (0.0005)

4 (0.0007)

  

 170

0 (0.0000)

5 (0.0002)

  

0 (0.0000)

0 (0.0000)

  

 180

0 (0.0000)

2 (0.0001)

  

0 (0.0000)

0 (0.0000)

  

 190

0 (0.0000)

0 (0.0000)

  

0 (0.0000)

0 (0.0000)

  

 ≥ 200

1 (0.0001)

2 (0.0001)

  

1 (0.0002)

0 (0.0000)

  

Sepsis

  

< 0.0001*

0.2190

  

0.7867

0.0048

 1

799 (0.0823)

953 (0.0318)

  

478 (0.0791)

470 (0.0778)

  

 0

8912 (0.9177)

28985 (0.9682)

  

5566 (0.9209)

5574 (0.9222)

  
  1. * P< 0.05