before propensity score matching | after propensity score matching | |||||||
---|---|---|---|---|---|---|---|---|
≥ 2 drugs (n = 9,711) | 1 drug (n = 29,938) | p | Standard mean difference | ≥ 2 drugs (n = 6,044) | 1 drug (n = 6,044) | p | Standard mean difference | |
Sex | < 0.0001* | 0.0985 | 0.5788 | 0.0100 | ||||
Male | 5683 (0.5861) | 16037 (0.5373) | 3561 (0.5892) | 3591 (0.5941) | ||||
Female | 4014 (0.4139) | 13809 (0.4627) | 2483 (0.4108) | 2453 (0.4059) | ||||
Age (year) | < 0.0001* | 0.9991 | ||||||
< 10 | 669 (0.0693) | 1671 (0.0563) | 358 (0.0592) | 363 (0.0601) | ||||
10 | 462 (0.0479) | 1183 (0.0399) | 285 (0.0472) | 265 (0.0438) | ||||
20 | 477 (0.0494) | 1586 (0.0534) | 238 (0.0394) | 225 (0.0372) | ||||
30 | 599 (0.0621) | 2367 (0.0797) | 344 (0.0569) | 341 (0.0564) | ||||
40 | 723 (0.0749) | 2186 (0.0736) | 455 (0.0753) | 448 (0.0741) | ||||
50 | 1256 (0.1302) | 3506 (0.1181) | 812 (0.1343) | 819 (0.1355) | ||||
60 | 2095 (0.2171) | 5787 (0.1949) | 1382 (0.2287) | 1399 (0.2315) | ||||
70 | 2195 (0.2275) | 6903 (0.2325) | 1476 (0.2442) | 1485 (0.2457) | ||||
80 | 1047 (0.1085) | 3821 (0.1287) | 636 (0.1052) | 643 (0.1064) | ||||
90 | 122 (0.0126) | 669 (0.0225) | 57 (0.0094) | 55 (0.0091) | ||||
100 | 3 (0.0003) | 7 (0.0002) | 1 (0.0002) | 1 (0.0002) | ||||
Height (cm) | < 0.0001* | 0.9998 | ||||||
< 10 | 0 (0.0000) | 0 (0.0000) | 0 (0.0000) | 0 (0.0000) | ||||
10 | 0 (0.0000) | 1 (0.0001) | 0 (0.0000) | 0 (0.0000) | ||||
20 | 3 (0.0005) | 1 (0.0001) | 2 (0.0003) | 1 (0.0002) | ||||
30 | 31 (0.0050) | 19 (0.0010) | 15 (0.0025) | 15 (0.0025) | ||||
40 | 22 (0.0035) | 44 (0.0024) | 20 (0.0033) | 21 (0.0035) | ||||
50 | 21 (0.0034) | 44 (0.0024) | 20 (0.0033) | 26 (0.0043) | ||||
60 | 29 (0.0047) | 62 (0.0033) | 28 (0.0046) | 27 (0.0045) | ||||
70 | 52 (0.0084) | 111 (0.0060) | 48 (0.0079) | 47 (0.0078) | ||||
80 | 46 (0.0074) | 85 (0.0046) | 43 (0.0071) | 45 (0.0074) | ||||
90 | 53 (0.0085) | 88 (0.0047) | 49 (0.0081) | 51 (0.0084) | ||||
100 | 42 (0.0068) | 98 (0.0053) | 40 (0.0066) | 41 (0.0068) | ||||
110 | 42 (0.0068) | 114 (0.0061) | 42 (0.0069) | 39 (0.0065) | ||||
120 | 58 (0.0093) | 132 (0.0071) | 58 (0.0096) | 62 (0.0103) | ||||
130 | 102 (0.0164) | 403 (0.0217) | 99 (0.0164) | 88 (0.0146) | ||||
140 | 747 (0.1202) | 2449 (0.1319) | 727 (0.1203) | 723 (0.1196) | ||||
150 | 1889 (0.3038) | 5975 (0.3218) | 1847 (0.3056) | 1824 (0.3018) | ||||
160 | 2108 (0.3391) | 6222 (0.3351) | 2058 (0.3405) | 2084 (0.3448) | ||||
170 | 890 (0.1432) | 2477 (0.1334) | 868 (0.1436) | 871 (0.1441) | ||||
180 | 81 (0.0130) | 238 (0.0128) | 79 (0.0131) | 79 (0.0131) | ||||
190 | 1 (0.0002) | 4 (0.0002) | 1 (0.0002) | 0 (0.0000) | ||||
≥ 200 | 0 (0.0000) | 0 (0.0000) | 0 (0.0000) | 0 (0.0000) | ||||
Weight (kg) | 0.0003* | 0.9916 | ||||||
< 10 | 200 (0.0264) | 369 (0.0177) | 117 (0.0194) | 120 (0.0199) | ||||
10 | 264 (0.0348) | 620 (0.0298) | 162 (0.0268) | 165 (0.0273) | ||||
20 | 190 (0.0250) | 470 (0.0226) | 119 (0.0197) | 113 (0.0187) | ||||
30 | 597 (0.0787) | 1683 (0.0808) | 437 (0.0723) | 438 (0.0725) | ||||
40 | 1813 (0.2390) | 4929 (0.2366) | 1498 (0.2478) | 1492 (0.2469) | ||||
50 | 2213 (0.2917) | 6176 (0.2964) | 1844 (0.3051) | 1851 (0.3063) | ||||
60 | 1506 (0.1985) | 4135 (0.1985) | 1204 (0.1992) | 1212 (0.2005) | ||||
70 | 559 (0.0737) | 1672 (0.0802) | 457 (0.0756) | 465 (0.0769) | ||||
80 | 156 (0.0206) | 503 (0.0241) | 132 (0.0218) | 131 (0.0217) | ||||
90 | 47 (0.0062) | 157 (0.0075) | 44 (0.0073) | 32 (0.0053) | ||||
100 | 15 (0.0020) | 62 (0.0030) | 9 (0.0015) | 10 (0.0017) | ||||
110 | 12 (0.0016) | 19 (0.0009) | 10 (0.0017) | 6 (0.0010) | ||||
120 | 4 (0.0005) | 7 (0.0003) | 1 (0.0002) | 0 (0.0000) | ||||
130 | 0 (0.0000) | 3 (0.0001) | 0 (0.0000) | 0 (0.0000) | ||||
140 | 4 (0.0005) | 3 (0.0001) | 3 (0.0005) | 2 (0.0003) | ||||
150 | 3 (0.0004) | 11 (0.0005) | 3 (0.0005) | 3 (0.0005) | ||||
160 | 3 (0.0004) | 7 (0.0003) | 3 (0.0005) | 4 (0.0007) | ||||
170 | 0 (0.0000) | 5 (0.0002) | 0 (0.0000) | 0 (0.0000) | ||||
180 | 0 (0.0000) | 2 (0.0001) | 0 (0.0000) | 0 (0.0000) | ||||
190 | 0 (0.0000) | 0 (0.0000) | 0 (0.0000) | 0 (0.0000) | ||||
≥ 200 | 1 (0.0001) | 2 (0.0001) | 1 (0.0002) | 0 (0.0000) | ||||
Sepsis | < 0.0001* | 0.2190 | 0.7867 | 0.0048 | ||||
1 | 799 (0.0823) | 953 (0.0318) | 478 (0.0791) | 470 (0.0778) | ||||
0 | 8912 (0.9177) | 28985 (0.9682) | 5566 (0.9209) | 5574 (0.9222) |