Fig. 5
From: Identification of the toxic threshold of 3-hydroxybutyrate-sodium supplementation in septic mice
Impact of increasing doses of 3HB-Na on markers of inflammation. a Plasma levels of TNFĪ±. Relative mRNA expression of Tnf measured in bĀ kidney, cĀ liver and dĀ hippocampus. a-d Number (n) of animals: white, healthy (nā=ā14); dashes, PNā+āglucose (nā=ā15); PNā+ā3HB-Na: black, 150Ā mg/d (nā=ā16); gray, 180Ā mg/d (nā=ā12); dark gray, 225/300Ā mg/d (nā=ā8). glc: glucose, PN: parenteral nutrition, mg/d: mg per day