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Table 1 Patient demographic and disease characteristics

From: Identification and solution of drug-related problems in the neurology unit of a tertiary hospital in China

Number Total
974 (100%)
With DRP 198 (20.3%) Without DRP 776 (79.7%)
Characteristics
 Sex, male 642 (65.9) 134 (67.7) 508 (65.5)
 Age 62.0 (54.0,70.0) 64.0 (55.0,73.0) 62.0 (53.0,69.0) **
 Smoke, currently 353 (36.2) 82 (41.4) 271 (34.9)
 Alcohol, currently 297 (30.5) 58 (29.3) 239 (30.8)
 Body mass index (kg/m2) 25.2 (23.1,27.5) 25.4 (23.5,26.9) 25.2 (23.0,27.6)
 Length of hospital stay, days 14.0 (11.0,15.0) 14.0 (11.0,15.0) 13.0 (11.0,15.0)
Admission diagnosis
 Cerebrovascular diseases a 704 (72.3) 156 (78.8) 548 (70.6) *
 Episodic and paroxysmal disorders b 64 (6.6) 11 (5.6) 53 (6.8)
 Disorders of the optic nerve and visual pathways c 65 (6.7) 8 (4.0) 57 (7.3)
 Demyelinating diseases of the central nervous system d 21 (2.2) 4 (2.0) 17 (2.2)
 Paralytic strabismus e 22 (2.3) 3 (1.5) 19 (2.4)
 Nerve, nerve root, and plexus disorders f 10 (1.0) 3 (1.5) 7 (0.9)
 Parkinson disease 5 (0.5) 2 (1.0) 3 (0.4)
 Myasthenia gravis 21 (2.2) 1 (0.5) 20 (2.6)
 Inflammatory diseases of the central nervous system g 10 (1.0) 2 (1.0) 8 (1.0)
 Polyneuropathies and other disorders of the peripheral nervous system h 7 (0.7) 1 (0.5) 6 (0.8)
 Others 32 (3.3) 7 (3.5) 25 (3.2)
Concomitant diseases
 Hyperlipidemia 807 (82.9) 168 (84.8) 639 (82.3)
 Hypertension 684 (70.2) 156 (78.8) 528 (68.0) **
 Diabetes 349 (35.8) 99 (50.0) 250 (32.2) ***
 Digestive system diseases 279 (28.6) 67 (33.8) 212 (27.3)
 Hyperhomocysteinemia (HCY) 154 (15.8) 38 (19.2) 116 (14.9)
 Liver dysfunction 128 (13.1) 34 (17.2) 94 (12.1)
 Coronary heart disease 127 (13.0) 25 (12.6) 102 (13.1)
 Sleep disorder 107 (11.0) 26 (13.1) 81 (10.4)
 Creatinine clearance (ml/min) 101.7 (80.3127.9) 94.6 (74.9121.4) 103.3 (80.8129.1) *
 Respiratory diseases 87 (8.9) 19 (9.6) 68 (8.8)
 Infectious diseases 74 (7.6) 36 (18.2) 38 (4.9) ***
 Hyperuricemia/gout 70 (7.2) 19 (9.6) 51 (6.6)
 Benign prostatic hyperplasia (BPH) 70 (7.2) 17 (8.6) 53 (6.8)
 Peripheral neuropathy 68 (7.0) 13 (6.6) 55 (7.1)
 Anxiety-depressive state 41 (4.2) 10 (5.1) 31 (4.0)
 Deep venous thrombosis (DVT) 37 (3.8) 12 (6.1) 25 (3.2)
 Atrial fibrillation 26 (2.7) 13 (6.6) 13 (1.7) ***
  1. *p < 0.05; ** p < 0.005; *** p < 0.0001
  2. aCerebral infarction, cerebral ischemia, cerebral haemorrhage; b Transient ischemic attack, epilepsy, migraine; c Anterior ischemic optic neuropathy, optic neuritis; d Multiple sclerosis, neuromyelitis optica spectrum disease; e Abducens nerve paralysis; f Diabetic mononeuropathy, trigeminal paralysis; g Purulent meningoencephalitis, nonspecific cavernous sinusitis; h Ischemic peripheral neuropathy, Guillain-Barre syndrome