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Table 1 Patient demographic and disease characteristics

From: Identification and solution of drug-related problems in the neurology unit of a tertiary hospital in China

Number

Total

974 (100%)

With DRP 198 (20.3%)

Without DRP 776 (79.7%)

Characteristics

 Sex, male

642 (65.9)

134 (67.7)

508 (65.5)

 Age

62.0 (54.0,70.0)

64.0 (55.0,73.0)

62.0 (53.0,69.0) **

 Smoke, currently

353 (36.2)

82 (41.4)

271 (34.9)

 Alcohol, currently

297 (30.5)

58 (29.3)

239 (30.8)

 Body mass index (kg/m2)

25.2 (23.1,27.5)

25.4 (23.5,26.9)

25.2 (23.0,27.6)

 Length of hospital stay, days

14.0 (11.0,15.0)

14.0 (11.0,15.0)

13.0 (11.0,15.0)

Admission diagnosis

 Cerebrovascular diseases a

704 (72.3)

156 (78.8)

548 (70.6) *

 Episodic and paroxysmal disorders b

64 (6.6)

11 (5.6)

53 (6.8)

 Disorders of the optic nerve and visual pathways c

65 (6.7)

8 (4.0)

57 (7.3)

 Demyelinating diseases of the central nervous system d

21 (2.2)

4 (2.0)

17 (2.2)

 Paralytic strabismus e

22 (2.3)

3 (1.5)

19 (2.4)

 Nerve, nerve root, and plexus disorders f

10 (1.0)

3 (1.5)

7 (0.9)

 Parkinson disease

5 (0.5)

2 (1.0)

3 (0.4)

 Myasthenia gravis

21 (2.2)

1 (0.5)

20 (2.6)

 Inflammatory diseases of the central nervous system g

10 (1.0)

2 (1.0)

8 (1.0)

 Polyneuropathies and other disorders of the peripheral nervous system h

7 (0.7)

1 (0.5)

6 (0.8)

 Others

32 (3.3)

7 (3.5)

25 (3.2)

Concomitant diseases

 Hyperlipidemia

807 (82.9)

168 (84.8)

639 (82.3)

 Hypertension

684 (70.2)

156 (78.8)

528 (68.0) **

 Diabetes

349 (35.8)

99 (50.0)

250 (32.2) ***

 Digestive system diseases

279 (28.6)

67 (33.8)

212 (27.3)

 Hyperhomocysteinemia (HCY)

154 (15.8)

38 (19.2)

116 (14.9)

 Liver dysfunction

128 (13.1)

34 (17.2)

94 (12.1)

 Coronary heart disease

127 (13.0)

25 (12.6)

102 (13.1)

 Sleep disorder

107 (11.0)

26 (13.1)

81 (10.4)

 Creatinine clearance (ml/min)

101.7 (80.3127.9)

94.6 (74.9121.4)

103.3 (80.8129.1) *

 Respiratory diseases

87 (8.9)

19 (9.6)

68 (8.8)

 Infectious diseases

74 (7.6)

36 (18.2)

38 (4.9) ***

 Hyperuricemia/gout

70 (7.2)

19 (9.6)

51 (6.6)

 Benign prostatic hyperplasia (BPH)

70 (7.2)

17 (8.6)

53 (6.8)

 Peripheral neuropathy

68 (7.0)

13 (6.6)

55 (7.1)

 Anxiety-depressive state

41 (4.2)

10 (5.1)

31 (4.0)

 Deep venous thrombosis (DVT)

37 (3.8)

12 (6.1)

25 (3.2)

 Atrial fibrillation

26 (2.7)

13 (6.6)

13 (1.7) ***

  1. *p < 0.05; ** p < 0.005; *** p < 0.0001
  2. aCerebral infarction, cerebral ischemia, cerebral haemorrhage; b Transient ischemic attack, epilepsy, migraine; c Anterior ischemic optic neuropathy, optic neuritis; d Multiple sclerosis, neuromyelitis optica spectrum disease; e Abducens nerve paralysis; f Diabetic mononeuropathy, trigeminal paralysis; g Purulent meningoencephalitis, nonspecific cavernous sinusitis; h Ischemic peripheral neuropathy, Guillain-Barre syndrome