|
Dosage (mg/kg)
|
Heart (%)
|
Liver (%)
|
Spleen (%)
|
Lung (%)
|
Kidney (%)
|
|---|
|
0
|
0.466 ± 0.002
|
4.800 ± 0.373
|
0.387 ± 0.079
|
0.588 ± 0.057
|
1.282 ± 0.140
|
|
703
|
0.463 ± 0.018
|
5.010 ± 0.558
|
0.406 ± 0.092
|
0.553 ± 0.069
|
1.227 ± 0.203
|
|
1406
|
0.429 ± 0.028
|
4.740 ± 0.295
|
0.422 ± 0.063
|
0.645 ± 0.097
|
1.162 ± 0.100
|
|
2812
|
0.454 ± 0.017
|
4.453 ± 0.242
|
0.398 ± 0.075
|
0.667 ± 0.031
|
1.198 ± 0.131
|
|
5628
|
0.473 ± 0.046
|
4.575 ± 0.173
|
0.394 ± 0.042
|
0.625 ± 0.024
|
1.320 ± 0.073
|
|
11,250
|
0.442 ± 0.053
|
5.877 ± 0.309**
|
0.288 ± 0.065**
|
0.697 ± 0.090**
|
1.249 ± 0.110
|
- Note: *P < 0.05 vs Normal, **P < 0.01 vs Normal
