Table 7 Effect of berberine hydrochloride on organ indexes in ICR mice by iUDP
Dosage (mg/kg) | Heart (%) | Liver (%) | Spleen (%) | Lung (%) | Kidney (%) |
|---|---|---|---|---|---|
0 | 0.466 ± 0.002 | 4.800 ± 0.373 | 0.387 ± 0.079 | 0.588 ± 0.057 | 1.282 ± 0.140 |
790 | 0.472 ± 0.028 | 4.602 ± 0.295 | 0.363 ± 0.063 | 0.580 ± 0.097 | 1.100 ± 0.100 |
2500 | 0.449 ± 0.045 | 4.472 ± 0.207 | 0.427 ± 0.096 | 0.627 ± 0.108 | 1.280 ± 0.073 |
5000 | 0.465 ± 0.039 | 4. 503 ± 0.200 | 0.426 ± 0.041* | 0.598 ± 0.049 | 1.129 ± 0.068 |