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Table 6 List of top-regulated genes in the miRNA-mRNA regulatory network

From: Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells

Gene name

Description

Degree

Regulated

YPEL2

protein yippee-like 2

5

down

TP53INP1

tumor protein p53-inducible nuclear protein 1

5

down

XYLT1

xylosyltransferase 1

4

down

ZC3H6

zinc finger CCCH domain-containing protein 6

4

down

NR5A2

nuclear receptor subfamily 5 group A member 2

4

down

PPP2R2C

serine/threonine-protein phosphatase 2A subunit B gamma isoform

3

down

FAIM2

Fas apoptotic inhibitory molecule 2

3

down

EPHA4

ephrin type-A receptor 4

3

down

YPEL1

protein yippee-like 1

3

down

THBS1

thrombospondin-1

5

up

CD44

CD44 antigen

3

up

IGFBP5

insulin like growth factor binding protein 5

3

up

ITGA3

integrin subunit alpha 3

3

up

WDR43

WD repeat-containing protein 43

3

up