Analysis of lung cancer-related genetic changes in long-term and low-dose polyhexamethylene guanidine phosphate (PHMG-p) treated human pulmonary alveolar epithelial cells

Table 1 Overview of common gene expression level changes in PHMG-p short-term treated HPAEpiCs and their reported expression changes in lung cancer

Gene symbol	Entrez ID	Description	Biotype	Fold change (FC)*			Expression	Reference(s)
Gene symbol	Entrez ID	Description	Biotype	#2/#1	#4/#3	#6/#5	Expression	Reference(s)
SNORD95	619570	small nucleolar RNA, C/D box 95	snoRNA	6,000	8,540	8,720	Up	[20]
MT1G	4495	metallothionein 1G	protein coding	6.15	3.92	2.93	Up	[21, 22]
MT1G	4495	metallothionein 1G	protein coding	6.15	3.92	2.93	Dn	[23]
CDC37L1-AS1	101929351	CDC37L1 antisense RNA 1 (head-to-head)	lncRNA	2.06	4.35	2.43	-	-
SNORA5A	654319	small nucleolar RNA, H/ACA box 5A	snoRNA	35.0	2.10	62.7	-	-
SNORA75	654321	small nucleolar RNA, H/ACA box 75	snoRNA	0.0328	0.0290	0.0533	Up	[20, 24]
SNORA28	677811	small nucleolar RNA, H/ACA box 28	snoRNA	0.0367	0.0169	0.0105	-	-
NARR	100861437	nine-amino acid residue-repeats	protein coding	0.479	0.289	0.349	-	-

(Dn: Down), (*: The FC value is provided as whole number, and the number of significant figures is specified as three.)

ISSN: 2050-6511