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Table 3 The number of living cells of MDA-MB-231 line after the action of “Activegel”

From: Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models

% of conditioned nutrient medium

MDA-MB-231 + saline solution

MDA-MB-231 + “Activegel”

№1

№2

№3

№1

№2

№3

Number of living cells, %

 

48 h

100

100.4 ± 1.8

102.7 ± 3.2

103.6 ± 3.5

104.3 ± 3.9

102.2 ± 4.3

99.7 ± 3.8

50

104.0 ± 4.4

106.1 ± 0.2

98.0 ± 0.9

100.4 ± 3.7

101.8 ± 4.7

101.9 ± 2.4

25

101.6 ± 3.5

103.3 ± 3.1

102.0 ± 3.1

103.1 ± 2.9

103.3 ± 2.8

100.5 ± 2.1

12.5

100.7 ± 0.9

100.8 ± 5.0

99.6 ± 4.4

101.5 ± 3.8

103.9 ± 4.1

100.8 ± 3.1

6.3

101.9 ± 1.0

102.5 ± 3.5

101.0 ± 2.8

101.0 ± 3.8

103.4 ± 1.9

99.6 ± 1.8

3.1

103.2 ± 2.6

102.1 ± 2.8

101.7 ± 3.4

100.6 ± 2.3

103.2 ± 1.8

102.8 ± 2.6

1.6

104.4 ± 2.2

103.3 ± 2.3

99.3 ± 1.8

99.6 ± 0.7

100.9 ± 3.1

100.5 ± 1.6

 

96 h

100

100.8 ± 2.3

100.0 ± 3.0

101.7 ± 3.7

98.3 ± 1.1

100.4 ± 3.6

99.1 ± 3.2

50

99.0 ± 4.1

99.7 ± 1.6

100.1 ± 5.0

100.9 ± 4.1

102.1 ± 3.1

101.4 ± 2.7

25

100.9 ± 3.6

98.7 ± 3.0

104.6 ± 1.5

102.7 ± 2.5

103.1 ± 2.0

101.1 ± 5.0

12.5

101.7 ± 3.2

100.6 ± 0.9

103.7 ± 2.6

102.5 ± 3.0

103.1 ± 1.5

102.7 ± 2.4

6.3

99.5 ± 1.8

100.9 ± 1.9

101.5 ± 3.6

102.7 ± 3.8

101.4 ± 2.9

101.0 ± 2.2

3.1

102.8 ± 2.9

100.6 ± 4.0

102.5 ± 1.9

102.4 ± 3.6

99.0 ± 2.9

102.3 ± 2.6

1.6

98.3 ± 2.5

102.9 ± 2.2

99.9 ± 2.6

101.1 ± 2.1

99.6 ± 1.2

98.7 ± 3.1