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Table 4 The number of living cells of MCF-7 line after the action of “Activegel”

From: Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models

% of conditioned nutrient medium

MCF-7 + saline solution

MCF-7 + “Activegel”

№1

№2

№3

№1

№2

№3

Number of living cells, %

 

48 h

100

101.3 ± 2.3

97.2 ± 1.5

100.3 ± 0.5

101.5 ± 2.4

101.1 ± 3.0

99.0 ± 1.7

50

99.9 ± 0.8

99.9 ± 2.3

98.7 ± 1.6

100.0 ± 0.9

100.6 ± 2.7

105.0 ± 1.8

25

99.9 ± 2.9

100.3 ± 3.2

102.3 ± 2.7

98.1 ± 1.1

101.2 ± 1.4

100.2 ± 0.7

12.5

100.8 ± 1.9

99.6 ± 0.5

99.2 ± 1.8

100.3 ± 3.2

99.3 ± 3.6

101.0 ± 1.8

6.3

101.7 ± 3.2

101.3 ± 2.9

100.0 ± 1.9

99.7 ± 2.0

101.8 ± 4.2

102.6 ± 2.2

3.1

99.3 ± 2.5

102.2 ± 3.1

99.9 ± 1.5

101.6 ± 1.4

99.2 ± 1.5

101.4 ± 2.7

1.6

99.3 ± 2.8

101.6 ± 1.1

98.7 ± 1.4

100.1 ± 2.2

101.9 ± 2.3

98.7 ± 3.7

 

96 h

100

100.3 ± 2.0

99.6 ± 2.1

100.3 ± 1.8

99.8 ± 3.1

99.1 ± 1.0

99.4 ± 3.1

50

102.2 ± 2.1

99.0 ± 3.4

99.7 ± 0.5

101.0 ± 3.1

99.2 ± 1.7

100.4 ± 2.7

25

99.5 ± 2.1

101.0 ± 1.3

103.5 ± 1.3

100.0 ± 1.0

101.3 ± 1.3

100.1 ± 0.4

12.5

101.0 ± 2.2

102.0 ± 2.1

100.8 ± 2.6

102.8 ± 1.4

98.4 ± 1.2

101.9 ± 2.8

6.3

100.5 ± 2.0

102.0 ± 2.2

101.2 ± 1.9

99.4 ± 2.9

102.3 ± 3.3

101.7 ± 2.9

3.1

101.3 ± 2.9

103.2 ± 1.6

100.9 ± 2.8

99.7 ± 1.5

100.0 ± 0.2

103.2 ± 2.3

1.6

98.3 ± 3.7

104.0 ± 3.0

103.4 ± 2.2

98.0 ± 2.2

99.2 ± 1.2

99.0 ± 2.5