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Table 1 Levels of MDA and CAT, SOD, GPx and caspase-3 activities 4 h after testicular detorsion

From: Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study

Group

MDA

(nmol/g wet tissue)

CAT

(IU/g wet tissue)

SOD

(IU/g wet tissue)

GPx

(IU/g wet tissue)

caspase-3

(ng/ml)

Control

116.09 ± 5.43***

354.19 ± 9.64***

1955.23 ± 10.70***

706.53 ± 32.26***

0.275 ± 0.024***

T/D

183.02 ± 18.26

264.71 ± 19.53

1581.13 ± 45.01

562.63 ± 31.99

0.523 ± 0.016

CsA 1

155.03 ± 10.08***

276.35 ± 10.28

1722.82 ± 41.54***

615.16 ± 15.44*

0.425 ± 0.024***

CsA 5

133.45 ± 5.27***,†

300.71 ± 13.51*,†

1752.49 ± 43.73***

630.20 ± 25.31***

0.363 ± .028***,φφφ

Nort 2

162.50 ± 9.24***

267.24 ± 9.09

1681.14 ± 17.01***

604.49 ± 8.38*

0.430 ± 0.037***

Nort 10

147.54 ± 5.27***,†

290.71 ± 12.58*,†

1736.49 ± 45.78***

625.10 ± 14.48***

0.342 ± .028***,φφφ

CsA 1 + Nort 2

158.30 ± 2.46***

281.20 ± 7.50*,†

1758.89 ± 44.87***

625.40 ± 21.32***

0.330 ± .029***

  1. *p < 0.05 compared with T/D group
  2. *** P < 0.001 compared with T/D group
  3. † P < 0.05 compared with CsA1mg/kg
  4. φφφ P < 0.001 compared with 1 mg/kg
  5. (n = 6)