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Table 5 Comparison of minor adverse effects between the two study groups

From: The effectiveness of pregabalin with or without agomelatine in the treatment of chronic low back pain: a double-blind, placebo-controlled, randomized clinical trial

Adverse effect

Pregabalin ± Placebo

(n = 23)

Pregabalin ± agomelatine

(n = 23)

P-Value

Nausea

5 (21.7)

6 (26)

0.73

Headache

2 (8.7)

3 (13)

0.63

Sleep disorder

6 (26)

9 (39)

0.34

Lightheadedness

3 (13)

3 (13)

-

Palpitation

2 (8.7)

2 (8.7)

-

Diarrhea

1 (4.3)

1 (4.3)

-

Muscle pain

2 (8.7)

3 (13)

0.63

  1. Data are demonstrated as number (%). A P < 0.05 is considered significant