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Table 2 Primary outcomes: examination score of all-risk ratings of common drug-drug interactions

From: Factors associated with a basic common drug-drug interaction knowledge among emergency department medical personnel

Variables

Examination score of all-risk ratings (total of 40 points) a

Unadjusted

Adjusted

Mean difference (95% CI)

p-value*

Mean difference (95% CI)

p-value*

Profession

     

 Emergency physician (EP)

20.3 ± 3.9

3.3

(2.1 to 4.5)

< 0.001

3.3

(1.8 to 4.7)

< 0.001

 Emergency medicine resident (EMR)

19 ± 4.3

2.1

(0.7 to 3.5)

0.005

2.5

(0.6 to 4.3)

0.010

 Emergency care nurse (ECN)

17 ± 4.4

Ref

 

Ref

 

Emergency medicine experience

     

 < 2 years

18.9 ± 4.3

Ref

 

Ref

 

 2–4 years

18.6 ± 4.5

-0.3

(-2.1 to 1.5)

0.743

0.1

(-1.7 to 1.8)

0.933

 ≥ 4 years

19.1 ± 4.4

0.2

(-1.4 to 1.8)

0.808

0.2

(-1.7 to 2)

0.864

Clinically pharmacological or toxicological training

     

 Never training

19 ± 4.2

Ref

 

Ref

 

 Ever training

18.7 ± 4.9

-0.2

(-1.6 to 1.1)

0.713

-1.3

(-2.6 to 0.1)

0.056

Last completed or recertified ACLS training

     

 Never training

15.3 ± 4

Ref

 

Ref

 

 < 2 years

19 ± 4.1

3.7

(0.7 to 6.6)

0.015

2.2

(-0.8 to 5.2)

0.153

 2–4 years

18.8 ± 4.6

3.4

(0.4 to 6.5)

0.027

2

(-1.1 to 5.2)

0.203

 ≥ 4 years

19.7 ± 4.8

4.4

(1.2 to 7.6)

0.007

3.3

(0.1 to 6.6)

0.042

Drug-drug interaction checker book use experience

     

 Never use

18.6 ± 4.6

Ref

 

Ref

 

 Ever use

19.6 ± 3.9

1

(-0.2 to 2.2)

0.108

1

(-0.2 to 2.2)

0.116

Drug-drug interaction checker application use experience

     

 Never use

18.2 ± 4.6

Ref

 

Ref

 

 Ever use

19.9 ± 3.8

1.7

(0.6 to 2.8)

0.003

0.5

(-0.8 to 1.7)

0.470

  1. Abbreviations: ACLS, advanced cardiovascular life support; Ref, reference; 95% CI, 95% confidence interval
  2. * p-value < 0.05 is statistically significant
  3. a Mean ± standard deviation and mean difference between groups were analyzed by regression analysis of means