Factors associated with a basic common drug-drug interaction knowledge among emergency department medical personnel

Table 3 Secondary outcomes: examination score of risk ratings X, D, and C of common drug-drug interactions

Variables	Examination score of risk ratings X, D and C (total of 20 points) ^a	Unadjusted		Adjusted
Variables		Mean difference (95% CI)	p-value*	Mean difference (95% CI)	p-value*
Profession
Emergency physician (EP)	6.7 ± 2.3	-0.2 (-0.9 to 0.5)	0.571	-0.3 (-1.1 to 0.6)	0.516
Emergency medicine resident (EMR)	6.3 ± 2.1	-0.6 (-1.5 to 0.2)	0.133	-0.9 (-2.0 to 0.2)	0.117
Emergency care nurse (ECN)	6.9 ± 2.7	Ref		Ref
Emergency medicine experience
< 2 years	7.0 ± 1.8	Ref		Ref
2–4 years	6.5 ± 2.4	-0.5 (-1.5 to 0.5)	0.332	-0.7 (-1.8 to 0.3)	0.155
≥ 4 years	6.7 ± 2.5	-0.3 (-1.2 to 0.6)	0.558	-0.8 (-1.9 to 0.3)	0.147
Clinically pharmacological or toxicological training
Never training	6.8 ± 2.4	Ref		Ref
Ever training	6.4 ± 2.3	-0.4 (-1.2 to 0.3)	0.221	-0.3 (-1.1 to 0.4)	0.367
Last completed or recertified ACLS training
Never training	6.8 ± 3.7	Ref		Ref
< 2 years	6.6 ± 2.2	-0.2 (-1.8 to 1.4)	0.796	0.4 (-1.4 to 2.1)	0.662
2–4 years	6.8 ± 2.3	0.1 (-1.6 to 1.7)	0.950	0.9 (-1.0 to 2.7)	0.349
≥ 4 years	6.8 ± 2.7	0 (-1.8 to 1.7)	0.987	0.5 (-1.3 to 2.4)	0.584
Drug-drug interaction checker book use experience
Never use	6.5 ± 2.4	Ref		Ref
Ever use	7.0 ± 2.3	0.5 (-0.2 to 1.1)	0.168	0.5 (-0.2 to 1.2)	0.161
Drug-drug interaction checker application use experience
Never use	6.7 ± 2.5	Ref		Ref
Ever use	6.7 ± 2.3	0.1 (-0.6 to 0.7)	0.827	0.1 (-0.6 to 0.9)	0.706

Abbreviations: ACLS, advanced cardiovascular life support; Ref, reference; 95% CI, 95% confidence interval
* p-value < 0.05 is statistically significant
^a Mean ± standard deviation and mean difference between groups were analyzed by regression analysis of means

ISSN: 2050-6511