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Table 5 Univariable and multivariable analyzes of factors associated with pDDIs

From: Potential drug-drug interactions and associated factors among admitted patients with psychiatric disorders at selected hospitals in Northwest Ethiopia

Variables

Category

Potential Drug-drug interaction

COR (95% CI)

AOR (95% CI)

P-value

No

Yes

Age (Years)

18–30

22

67

1

1

 

31–45

43

72

0.55(0.13–1.89)

0.39(0.17–2.65)

 

46–60

27

44

0.54(0.09–1.02)

0.36(0.12–1.86)

 

≥ 61

9

41

1.5(1.01–2.65)

1.47(1.13–2.56)

0.043*

Sex

Male

49

104

1

1

 

Female

52

120

0.92(0.24–2.16)

1.48(0.96–2.28)

0.62

Source of medication

Free

Payment

61

40

134

90

1

0.98(0.17–2.04)

1

1.24(0.72–2.11)

0.429

Presence of Comorbidities

No

36

107

1

1

 

1–2

21

47

1.33(0.76–2.25)

1.74(0.90–3.36)

0.098

3–4

32

61

1.56(0.28–4.74)

1.12(0.74–2.47)

0.076

≥ 5

12

9

3.96(0.32–18.45)

1.16(0.98–2.13)

0.087

Number of prescribed medications

< 5

≥ 5

56

45

128

96

1

1.07(1.002–1.761)

1

2.75(1.56–7.31)

0.035*

Duration of treatment

≤ 1 year

2–3 years

≥ 4 years

56

25

20

120

61

43

1

0.88(0.15–2.67)

0.99(0.25–2.61)

1

0.67(0.35–1.40)

0.83(0.35–1.78)

0.31

0.57

Length of hospital stay

< 7days

≥ 7 days

85

16

205

19

1

2.03(0.56–3.12)

1

2.13(1.34–3.64)

0.004*

  1. COR Crude odds ratio, AOR Adjusted odds ratio
  2. *denotes statistically significant at p < 0.05