Fig. 4

CXB enhanced autophagy in a dose-dependent manner. A, B NPCs were treated with IL-1β alone or with 0.2, 2, 5, 10 µM of CXB and analyzed with LC3-II/LC3-I, p62, ATG5, and Beclin-1. C, D NPCs were treated with IL-1β alone or with 10 µM CXB. Furthermore, 200nM Baf A1 was added to confirm autophagosome enhancement by inhibiting autophagosome formation. The grouping of blots were cropped from different parts of different blots. Data were represented as mean with SD. *P ≤ 0.05, **P ≤ 0.01, *** P ≤ 0.001