Fig. 1

Open Field Test results of WIN55, 212–2 treated mice versus controls. The number of lines crossed (A), the number of central square entries (B), and the duration in the central square (C) in the groups studied are displayed. Mean ± SD are shown. Statistical differences were determined by two-way ANOVA (analysis of variance). Post-hoc test (Least Significant Difference; LSD) was carried out to determine differences between groups. ^aStatistically significant as compared to the female -ve controls. ^bStatistically significant as compared to the female vehicle group (saline and DMSO). ^cStatistically significant as compared to the female low dose group (0.05 mg/kg). ^dStatistically significant as compared to the female high dose group (0.1 mg/kg). ^eStatistically significant as compared to the male -ve controls. ^fStatistically significant as compared to the male vehicle group (saline and DMSO). ^gStatistically significant as compared to the male low dose  group (0.05mg/kg).