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Table 1 Kidney and liver function tests

From: Sea urchin (Diadema savignyi) extract as a novel protective agent against cisplatin induced neurotoxicity in rats

 

Creatinine

Urea

ALT

AST

Control

0.4483 ± 0.039b

44.94 ± 0.065b

45.22 ± 0.685b

79.8 ± 0.2b

SEM ± 0.022

SEM ± 0.037

SEM ± 0.306

SEM ± 0.089

Cisplatin

0.974 ± 0.024a

145.5 ± 0.51a

88.91 ± 0.91a

145.8 ± 0.55a

SEM ± 0.014

SEM ± 0.28

SEM ± 0.407

SEM ± 0.246

SH 100

0.4967 ± 0.025b

33.88 ± 0.12a,b

39.99 ± 0.99b

74.5 ± 0.5b

SEM ± 0.013

SEM ± 0.069

SEM ± 0.44

SEM ± 0.226

SH 50

0.5077 ± 0.026b

30.65 ± 0.65a,b

41.65 ± 0.65b

86.8 ± 0.2a,b

SEM ± 0.015

SEM ± 0.37

SEM ± 0.290

SEM ± 0.083

SP 100

0.5543 ± 0.038b

32.7 ± 0.69a,b

40.73 ± 0.725b

76.87 ± 0.41b

SEM ± 0.022

SEM ± 0.40

SEM ± 0.324

SEM ± 0.21

SP 50

0.5073 ± 0.015b

31.78 ± 0.71a,b

43.5 ± 0.51b

86.4 ± 0.56a,b

SEM ± 0.018

SEM ± 0.44

SEM ± 0.223

SEM ± 0.25

  1. Data is expressed as mean ± SD, and Standard error of the mean SEM
  2. aSignificant compared to the control group; p-value < 0.0001. bSignificant compared to the Cisplatin model group; p-value < 0.0001