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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: miR-34a/DRP-1-mediated mitophagy participated in cisplatin-induced ototoxicity via increasing oxidative stress

Fig. 5

MiR-34a modulated DRP1 expression and mitophagy in HEI-OC1 cells. A The putative binding site of miR-34a-5p on the 3’-UTR of DRP1 as predicted in the TargetScan database. B, C qRT‒PCR showed the level of miR34a in HEI-OC1 cells transfected with miR-34a mimic inhibitor or control. D-F Western blot analysis showed DRP1 and LC3-II/I expression in HEI-OC1 cells after miR34a mimic, inhibitor or control transfection

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