Table 5 Population simulation results of 20 mg atorvastatin tablets

C_max (µg/L)

89.34

(83.11, 95.26)

82.70

(75.92, 88.79)

to

96.51

(90.98, 102.48)

AUC_0–∞(µg·h/L)

90.58

(86.92, 93.43)

83.67

(79.53, 86.29)

to

98.07

(95.01, 101.16)

AUC_0–t (µg·h/L)

90.57

(86.91, 93.42)

84.05

(79.96, 86.87)

to

97.61

(94.47, 100.47)

In silico BE judgment

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