Antibiotics and antibiotic-associated diarrhea: a real-world disproportionality study of the FDA adverse event reporting system from 2004 to 2022

Table 1 Two-by-two contingency table for disproportional analysis

	AAD	All other adverse drug reactions	Total
antibiotics	a	b	a + b
Other drugs	c	d	c + d
Total	a + c	b + d	a + b + c + d

ROR = ad/bc, 95%CI = e^ln(ROR).^±1.96 \(\sqrt{\frac{1}{\mathrm{a}}}+\frac{1}{\mathrm{b}}+\frac{1}{\mathrm{c}}+\frac{1}{\mathrm{d}}\) (criteria: the lower 95%Cl > 1,a ≥ 3)
ROR Reporting odds ratio, AAD Antibiotic-associated diarrhea.

ISSN: 2050-6511