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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: Metabolomic analysis of the serum and urine of rats exposed to diazinon, dimethoate, and cypermethrin alone or in combination

Fig. 1

Effect of pesticides diazinon (DZN), dimethoate (DIM), and cypermethrin (CYP) alone or in combination on the liver and kidneys of rats. The tissue sections of liver and kidneys of the rats were examined under a microscope. Compared with the control rats showing normal structure of liver (upper panel) and kidney tissues (bottom panel), the rats exposed to DZN (250 mg/kg body weight/day), DIM (300 mg/kg body weight/day), and CYP (500 mg/kg body weight/day) individual or in combination for 28 consecutive days exhibited swelling degeneration of hepatocytes in liver tissue (the red arrows indicate the hepatocyte necrosis) and abnormal glomerular capillary wall in kidney tissue (the black arrows indicate the glomerular lesions). Scale bar: 50 μm. Abbreviation: CTL, control; MIX, the mixture of DZN, DIM, and CYP

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