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Table 1 Effect of pesticides on serum biochemical parameters of rats (mean ± SD)

From: Metabolomic analysis of the serum and urine of rats exposed to diazinon, dimethoate, and cypermethrin alone or in combination

Parameters

Control

Diazinon

Dimethoate

Cypermethrin

Combination

SGOT (U/L)

156.5 ± 8.2

228.0 ± 20.4

206.5 ± 14.3

229.0 ± 21.8

255.2 ± 96.8*

SGPT (U/L)

62.0 ± 5.4

45.7 ± 3.9*

47.2 ± 6.5*

52.2 ± 5.5

58.5 ± 7.2

GLU (mM)

5.4 ± 0.1

5.7 ± 0.6

5.5 ± 0.2

4.4 ± 0.9*

5.0 ± 0.5

BUN (mM)

7.3 ± 1.4

7.5 ± 0.9

6.5 ± 0.7

5.6 ± 0.5*

4.8 ± 0.5*

ALP (U/L)

132.0 ± 16.6

157.5 ± 4.9

150.7 ± 9.8

137.2 ± 12.1

179.7 ± 46.7*

ALB (g/L)

33.0 ± 0.2

33.5 ± 0.9

32.8 ± 0.5

34.8 ± 1.9

35.7 ± 2.2

CRE (μM)

51.0 ± 4.2

55.5 ± 3.5

48.2 ± 6.4

39.5 ± 9.6

47.5 ± 7.5

  1. Notes: * P < 0.05, compared with the control (n = 6 for each group). Abbreviations: SGOT, serum glutamic-oxaloacetic transaminase; SGPT, serum glutamic-pyruvic transaminase; GLU, glucose; BUN, blood urea nitrogen; ALP, alkaline phosphatase; ALB, albumin; CRE, creatinine