Fig. 4
From: Dolutegravir-induced growth and lifespan effects in Caenorhabditis elegans
Effect of DTG on intracellular ROS accumulation level in worms. Worms were treated by DTG from early adulthood (Day 0) to Day 10 at different concentrations, and intracellular ROS levels were analyzed on the 10th day by staining with (A) DHE and (B) Mito-SOX. The intensity of emitted fluorescence was quantified as (C) and (D) respectively. The data shown represent the average of four independent experiments, and each experiment measured for 84 worms (mean ± SD, *p < 0.05; **p < 0.01; ***p < 0.001)