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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Dolutegravir-induced growth and lifespan effects in Caenorhabditis elegans

Fig. 5

Effect of NAC treatment on lifespan and ROS accumulation of nematodes exposed to 83 µg/ml of DTG. (A) After co-treatment with 83 µg/ml of DTG and 5mM NAC, intracellular ROS levels were analyzed on the 10th day by staining with Mito-SOX and quantified as (B). (C) Kaplan–Meier curves with univariate analyses for worms (n = 120). (D) Average survival days of three independent experiments were analyzed by (C) (mean ± SD, **p < 0.01; ***p < 0.001)

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