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Table 2 Effect of levocetrizine on inflammatory cell counts in BAL of rats

From: Levocetrizine attenuates cyclophosphamide-induced lung injury through inhibition of TNF-α, IL-1β, TGF-β and MMP-9

Groups

Total cell count × 104

Neutrophil (cell/lung) × 104

Lymphocytes (cell/lung) × 104

Eosinophils (cell/lung) × 104

Basophils (cell/lung) × 104

Control

8.3 ± 0.6

5.1 ± 0.4

2.8 ± 0. 2

0. 1 ± 0.01

0. 11 ± 0.01

CP

93.7 ± 2.1*

67. 1 ± 2.3*

22. 4 ± 1*

2.3 ± 0. 4*

1.87 ± 0.04*

CP/Levo

41 ± 1.1*$

24.6 ± 0.5*$

14.9 ± 0.6*$

0.8 ± 0.02$

0. 54 ± 0.07*$

  1. Values represent the mean of 5 rats ± SEM. * p < 0.05 vs. control; $ p < 0.05 vs. CP
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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