Fig. 2

Bar graphs showing the percentage relative abundance of significantly altered bacteria, (A) Ruminococcaceae, (B) Bacteroidaceae, (C) Bacteroides faecis, and (D) Bacteroides_u_s. (E) Intestinal and (F) Serum acetate levels (in mM) of both CHOW and MC mice groups are represented as bar graphs (ns – non significant, * p < 0.05, ** p < 0.01, *** p < 0.001). Data were represented as mean ± SEM and statistical significance was tested using unpaired t-test between the two groups followed by Bonferroni–Dunn post hoc corrections. Correlation plot between intestinal acetate concentration and relative abundances of the bacterial families (G) Ruminococcaceae and (H) Bacteroidaceae and bacterial species (I) Bacteroides faecis and (J) Bacteroides_u_s in the gut microbiome