Fig. 5
The effect of amlodipine on lipid peroxidation and inflammatory markers in renal I/R injury. I/R injury led to a significant increase in MDA (&&&, p < 0.001), TNF-α (&&&, p < 0.001) and IL1β (&&, p < 0.01) levels in tissue specimens. MDA (*, < 0.05), TNF-α (**, p < 0.01), and IL1β (*, p < 0.05) levels remarkably decreased after treatment with amlodipine. One-way analysis of variance (ANOVAs) followed by post hoc Tukey’s tests was used to compare the groups. Charts are shown as mean ± standard error of the mean (SEM) (n = 5)