Table 1 EGTI histology scoring system for renal ischemia/reperfusion injury defined by Chavez et al. 30
Tissue type | Damage | Score |
|---|---|---|
Tubular | No damage | 0 |
Loss of brush border (BB) in less than 25% of tubular cells. Integrity of basal membrane | 1 | |
Loss of BB in more than 25% of tubular cells, thickened basal membrane | 2 | |
(Plus) Inflammation, cast formation, necrosis up to 60% of tubular cells | 3 | |
(Plus) Necrosis in more than 60% of tubular cells | 4 | |
Endothelial | No damage | 0 |
Endothelial swelling | 1 | |
Endothelial disruption | 2 | |
Endothelial loss | 3 | |
Glomerular | No damage | 0 |
Thickening of Bowman capsule | 1 | |
Retraction of glomerular tuft | 2 | |
Glomerular fibrosis | 3 | |
Tubulointerstitial | No damage | 0 |
Inflammation, hemorrhage in less than 25% of tissue | 1 | |
Inflammation, hemorrhage in less than 25% of tissue plus necrosis in less than 25% of tissue | 2 | |
Necrosis up to 60% | 3 | |
Necrosis more than 60% | 4 |