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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: In diabetic male Wistar rats, quercetin-conjugated superparamagnetic iron oxide nanoparticles have an effect on the SIRT1/p66Shc-mediated pathway related to cognitive impairment

Fig. 2

Effect of QC and QCSPIONs treatment on diabetic rats’ hippocampal miR-34a and let-7a-5p levels (A) and (B). NDC stands for non-diabetic control, DC for diabetic control, DC + SPION for diabetic treatment using a superparamagnetic iron oxide nanoparticle, DC + QC for diabetic treatment using quercetin, and DC + QCSPION for diabetic treatment using a quercetin-conjugated iron oxide nanoparticle.* P < 0.05 and *** P < 0.001 and P < 0.0001 versus DC group (one-way ANOVA, Tukey’s multiple comparison tests). Mean values are expressed together with the standard error of the mean (SEM) (n = 5 per group)

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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