Fig. 2

Sex-biased drug-adverse event pairs in FAERS. (A) Volcano plot of the log-transformed reporting odds ratio (ROR) and the negative log-transformed Benjamini-Hochberg p-values from Fisher’s exact test of overlap of drug and SBAEs. (B) Overlap of drugs from male- and female-biased drug-adverse event pairs. (C) Overlap of adverse events from male- and female-biased drug-adverse event pairs. (D) Boxplot of the number of randomly selected drugs with SBAE drug targets. (E) Boxplot of the number of randomly selected drugs with SBAE drug enzyme. Green dot is the number of SBAE-associated drugs with drug target or drug enzyme