Fig. 2

The cumulative release rate of pexiganan for LLC-GDO in-vitro. Cla: Clarithromycin; Pex: Pexiganan; LLC-Pex: Lipid Liquid Crystal-Pexiganan. Our results suggest that both clarithromycin as well as pexiganan have initial burst release without vehicle; However, pexiganan incorporated within lipid-liquid crystal formulation has slow-release than with no vehicles. As shown, pexiganan and clarithromycin does reach to more than 90% of release before the initial 4 h; While, the lipid liquid crystal has controlled the release of pexignan. In this relation, there are 20% of loaded pexignan was released from lipid liquid crystal formulation