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Table 1 The impact of sub-lethal dose of pexiganan on biochemical and hematological parameters in mice

From: Sustain-release lipid-liquid crystal formulations of pexiganan against Helicobacter pylori infection: in vitro evaluation in C57BL/6 mice

Group

Urea (mg/dL)

Creatinine

(mg/dL)

AST

(U/L)

ALT

(U/L)

RBC

(106/µL)

WBC

(103/µL)

Control

47.39 ± 4.33

0.57 ± 3.25

77.63 ± 21.42

59.19 ± 21.37

9.27 ± 0.61

5.83 ± 0.02

Pexiganan

(10.7 mg/kg)

45.25 ± 7.51

0.58 ± 2.37

75.02 ± 23.63

57.23 ± 13.35

9.15 ± 0.89

5.13 ± 0.52

p-value

(t-test)

0.063

0.63

0.76

0.08

0.48

0.073

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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