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Table 1 Baseline patient characteristics

From: Large variation in anti-factor Xa levels with nadroparin as thromboprophylaxis in COVID-19 and non-COVID-19 critically ill patients

Characteristic

Total

n = 62

COVID-19

n = 30

Non-COVID-19

n = 32

Male sex (number, %)

37 (60%)

20 (67%)

17 (53%)

Age (years)

66 (59–72)

66 (59–73)

67 (57–71)

Length (cm)a

173 (169–178)

173 (169–179)

173 (169–178)

Weight (kg)

85 (70–105)

91 (76–109)

83 (68–94)

BMI (kg/m2)a

27.8 (24.3–32.0)

30.0 (25.6–35.6)

26.6 (22.2–29.7)

APACHE IV score

72 (59–90)

65 (56–74)

89 (69–103)

Diagnosis (number, %)

   

Pulmonary

41 (66%)

 

11 (35%)

of which COVID-19

30 (48%)

30 (100%)

 

Cardiovascular

7 (11%)

 

7 (22%)

Renal

3 (4.8%)

 

3 (9%)

Gastro-intestinal

2 (3.2%)

 

2 (6%)

Other

9 (15%)

 

9 (28%)

Comorbidity (number, %)

   

Hypertension

29 (47%)

14 (47%)

15 (47%)

MI/other cardiac diseases

19 (31%)

12 (40%)

7 (22%)

Diabetes Mellitus

16 (26%)

5 (17%)

11 (34%)

COPD/Asthma

15 (24%)

5 (17%)

10 (31%)

Morbid obesity

6 (9.7%)

4 (13%)

2 (6%)

CVA

5 (8.1%)

1 (3%)

4 (13%)

Chronic renal failure

4 (6.5%)

2 (7%)

2 (6%)

Malignancy

3 (4.8%)

1 (3%)

2 (6%)

None

3 (4.8%)

2 (7%)

1 (3%)

VTE (DVT/PE)

1 (1.6%)

-

1 (3%)

Other

52 (84%)

23 (77%)

29 (91%)

Laboratory values at baselineb

Creatinine (µmol/L)

76 (60–98)

65 (52–90)

87 (62–129)

Creatinine clearance (eGFR CKD-EPI, ml/min/1.73m2)

88 (64–98)

92 (70–102)

78 (43–95)

CRP (mg/L)

73 (25–193)

83 (53–167)

39 (4-277)

Hb (g/dL)

13.54 (11.60-14.18)

13.05 (11.28–14.02)

13.70 (11.76–14.99)

Platelet count (x109/L)

260 (181–344)

251 (178–372)

266 (181–339)

D-dimerc (µg/L)

-

2540 (928–5745)

-

  1. Data are medians with interquartile ranges in parentheses unless otherwise stated
  2. APACHE-IV = Acute Physiology And Chronic Health Evaluation-IV, BMI = Body Mass Index, COPD = Chronic Obstructive Pulmonary Disease, COVID-19 = Corona Virus Infectious Disease-2019, CRP = C-reactive Protein, CVA = Cerebro Vascular Accident, DVT = Deep Vein Thrombosis, eGFR CKD-EPI = Estimated Glomerular Filtration Rate calculated with the Chronic Kidney Disease Epidemiology Collaboration, Hb = Hemoglobin, MI = Myocardial Infarction, PE = Pulmonary Embolism, VTE = Venous ThromboEmbolism,
  3. a3 missing data
  4. bNormal ranges of measured laboratory tests were defined as follows:
  5. 53–97 µmol/L for creatinine, > 90 ml/min/1.73m2 for estimated Glomerular Filtration Rate calculated with the Chronic Kidney Disease Epidemiology Collaboration (eGFR CKD-EPI), < 4 mg/L for C-reactive protein (CRP), 11.92–15.95 mmol/L for women and 13.54–17.40 for men for hemoglobin (Hb) level, 150-400x109/L for platelet count, and < 500 µg/L for D-dimer level.
  6. conly 2 values of non-COVID-19 patients, 29 values of COVID-19 patient available