Table 4 Covariate regression analysis of factors related to anti-FXa levels

2850 IU

0.12 (0.05–0.19)

0.001

5700 IU*

+ 0.23 (0.12–0.35)

< 0.001

11400 IU*

+ 0.469 (0.331–0.606)

< 0.001

Baseline parameter

Gender^a

-0.07 (-0.17–0.03)

0.151

Age (years)^b

0.001 (-0.004–0.007)

0.601

Weight (kg)^b

-0.003 (-0.006– -0.001)

0.013

BMI (kg/m²)^b

-0.007 (-0.014–0.001)

0.083

COVID-19^a

-0.06 (-0.35–0.24)

0.700

APACHE IV score ^b

0.001 (-0.001–0.004)

0.210

Day of anti-FXa level

Cumulative fluid balance^b

8.95x10^− 6 (-3.95x10^− 5– 5.74 x 10^− 5)

0.713

Vasopressor use^a

-0.07 (-0.17–0.03)

0.173

eGFR^b

-0.001 (-0.002–0.0001)

0.147

CRP^b

0.000 (-0.001–0.000)

0.118