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Table 3 Pearson correlation coefficients among uranium levels/OxS parameters and kidney injury/inflammation biomarkers (n = 40; upper row: r; middle row: 95% CI; lower row: t, P)

From: Role of uranium toxicity and uranium-induced oxidative stress in advancing kidney injury and endothelial inflammation in rats

Biomarkers

Tissue U

Serum U

TOS

TAS

OSI

Ure

0.109

0.377

0.206

−0.143

0.162

(−0.210, 0.407)

(0.075, 0.616)

(−0.112, 0.487)

(−0.435, 0.177)

(−0.157, 0.451)

0.675, 0.504

2.511, 0.016

1.300, 0.201

−0.890, 0.379

1.014, 0.317

Cre

0.019

0.301

0.214

−0.207

0.196

(−0.294, 0.329)

(−0.012, 0.560)

(−0.105, 0.493)

(−0.487, 0.112)

(−0.123, 0.479)

0.120, 0.905

1.943, 0.060

1.350, 0.185

−1.302, 0.201

1.234, 0.225

CysC

0.282

0.501

0.306

−0.223

0.278

(−0.033, 0.545)

(0.225, 0.703)

(−0.006, 0.564)

(−0.500, 0.096)

(−0.037, 0.543)

1.809, 0.078

3.572, 0.001

1.980, 0.055

−1.408, 0.167

1.784, 0.083

NGAL

0.455

0.372

0.447

−0.398

0.457

(0.167, 0.671)

(0.069, 0.613)

(0.157, 0.666)

(−0.631, −0.099)

(0.169, 0.673)

3.148, 0.003

2.474, 0.018

3.077, 0.004

−2.672, 0.011

3.164, 0.003

CRP

0.196

0.178

0.431

−0.408

0.457

(−0.123, 0.479)

(−0.141, 0.464)

(0.138, 0.656)

(−0.641, −0.109)

(0.170, 0.673)

1.235, 0.224

1.117, 0.271

2.944, 0.006

−2.736, 0.009

3.170, 0.003

Lp-PLA2

−0.449

−0.414

−0.420

0.569

−0.493

(−0.667, −0.160)

(−0.642, −0.117)

(−0.647, −0.125)

(0.313, 0.748)

(-0.698, −0.215)

−3.096, 0.004

−2.801, 0.008

−2.856, 0.007

4.269, <0.001

−3.498, 0.001

Hcy

−0.344

−0.197

−0.226

0.396

−0.322

(−0.592, −0.037)

(−0.479, 0.122)

(−0.502, 0.092)

(0.096, 0.630)

(−0.566, 0.003)

−2.262, 0.030

−1.240, 0.223

−1.430, 0.161

2.658, 0.011

1.996, 0.053

  1. Notes Only NGAL and Lp-PLA2 were correlated with tissue U, serum U, and all OxS parameters
  2. Significance values are presented in bold