BMC Pharmacology and Toxicology

Table 4 Partial correlation coefficients between kidney injury/inflammation biomarkers and uranium content or OxS parameters (n = 40)

From: Role of uranium toxicity and uranium-induced oxidative stress in advancing kidney injury and endothelial inflammation in rats

Variables	Crude analysis			Adjusted analysis*
Variables	r_partial	t	P	r_partial	t	P
Tissue U
Ure	−0.112	−0.645	0.523	−0.232	−1.305	0.202
CysC	0.177	1.034	0.309	0.190	1.057	0.299
NGAL	0.455	3.148	0.003	0.455	3.148	0.003
Lp-PLA2	−0.167	−0.972	0.338	−0.032	−0.177	0.861
CRP	−0.088	−0.509	0.614	−0.251	−1.419	0.166
Hcy	−0.076	−0.437	0.665	−0.227	−1.276	0.212
Serum U
Ure	0.159	0.923	0.363	0.096	0.529	0.601
CysC	0.501	3.572	0.001	0.501	3.572	0.001
NGAL	0.147	0.855	0.399	0.014	0.078	0.938
Lp-PLA2	−0.116	−0.673	0.506	−0.014	−0.077	0.939
CRP	−0.114	−0.657	0.516	−0.218	−1.223	0.231
Hcy	−0.067	−0.388	0.700	−0.165	−0.915	0.368
TOS
Ure	0.041	0.237	0.814	0.078	0.438	0.664
CysC	0.029	0.168	0.868	−0.016	−0.090	0.929
NGAL	0.385	2.537	0.016	0.232	1.330	0.193
Lp-PLA2	0.365	2.388	0.022	0.391	2.586	0.014
CRP	−0.129	−0.744	0.462	−0.082	−0.459	0.650
Hcy	0.112	0.649	0.521	0.139	0.783	0.440
TAS
Ure	0.000	0.001	0.999	0.004	0.020	0.985
CysC	0.044	0.252	0.803	0.050	0.280	0.782
NGAL	−0.146	−0.846	0.404	−0.135	−0.757	0.455
Lp-PLA2	0.569	4.269	<0.001	0.569	4.269	<0.001
CRP	−0.169	−0.986	0.331	−0.171	−0.968	0.341
Hcy	−0.006	−0.035	0.973	−0.008	−0.045	0.965
OSI
Ure	−0.002	−0.012	0.991	0.019	0.105	0.917
CysC	0.006	0.036	0.972	−0.023	−0.128	0.899
NGAL	0.279	1.667	0.105	0.226	1.290	0.207
Lp-PLA2	−0.494	−3.498	0.001	−0.494	−3.498	0.001
CRP	0.283	1.694	0.100	0.299	1.746	0.091
Hcy	0.054	0.311	0.758	0.071	0.394	0.696

Note *Adjusted by the OxS parameters (if uranium content was the dependent variable) or by tissue/serum uranium content (if OxS parameter was the dependent variable). All the significant partial correlation coefficients were derived from the results of the Stepwise method, and no-significant partial correlation coefficients were derived from the results of the Enter method
Significance values are presented in bold

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