Comparison of three different prophylactic treatments for postoperative nausea and vomiting after total joint arthroplasty under general anesthesia: a randomized clinical trial

Table 2 Incidence of PONV during the first postoperative 48 h

	Group A (n = 108)	Group B (n = 108)	Group C (n = 116)	P*	p1^†	p2^†	p3^†
Total PONV	56(51.9%)	40(37.0%)	34(29.3%)	0.002	0.028	0.001	0.219
Vomiting	22 (20.4%)	17 (15.7%)	16 (13.8%)	0.401	-	-	-
Nausea	34 (31.5%)	23 (21.3%)	18 (15.5%)	0.016	0.086	0.005	0.264
Complete response	52 (48.2%)	68 (63.0%)	82 (70.7%)	0.002	0.028	0.001	0.219
Mild PONV	10 (9.3%)	6 (5.6%)	16 (13.8%)	0.112	-	-	-
Moderate PONV	18 (16.7%)	12 (11.1%)	13 (11.2%)	0.375	-	-	-
Severe PONV	28 (25.9%)	22 (20.4%)	5 (4.3%)	< 0.001	0.333	< 0.001	< 0.001
Moderate + severe PONV	46(42.6%)	34 (31.5%)	18 (15.5%)	< 0.001	0.082	< 0.001	0.005

Data are presented as number of patients (percentage)
PONV, postoperative nausea and vomiting
*Uncorrected p values (for the three-way comparison)
^†Bonferroni-corrected p values: p1, Group A vs. B; p2, Group A vs. C; p3, Group B vs. C. The corrected significance threshold was 0.016

ISSN: 2050-6511