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Table 3 Timing of PONV events during the first postoperative 48 h

From: Comparison of three different prophylactic treatments for postoperative nausea and vomiting after total joint arthroplasty under general anesthesia: a randomized clinical trial

Time

Total

(n = 332)

Group A

(n = 108)

Group B

(n = 108)

Group C

(n = 116)

p*

p1†

p2†

p3†

0–6 h

75 (22.6%)

19 (17.6%)

27 (25%)

29 (25%)

0.319

-

-

-

6–12 h

28 (8.4%)

15 (13.9%)

8 (7.4%)

5(4.3%)

0.032

0.123

0.012

0.322

12–24 h

17 (5.1%)

13 (12.0%)

4 (3.7%)

0

< 0.001

0.023

0.001

0.052

24–48 h

16 (4.8%)

13 (12.0%)

3 (2.8%)

0

< 0.001

0.009

< 0.001

0.110

  1. Data are presented as number of patients (percentage)
  2. PONV, postoperative nausea and vomiting
  3. *Uncorrected p values (for the three-way comparison)
  4. †Bonferroni-corrected p values: p1, Group A vs. B; p2, Group A vs. C; p3, Group B vs. C. The corrected significance threshold was 0.016
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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