Comparison of three different prophylactic treatments for postoperative nausea and vomiting after total joint arthroplasty under general anesthesia: a randomized clinical trial

Table 4 Duration of PONV during the first postoperative 48 h

Duration	Total (n = 332)	Group A (n = 108)	Group B (n = 108)	Group C (n = 116)	p*	p1^†	p2^†	p3^†
Mean time (h)	13.6 ± 5.4	16.2 ± 5.0	18.2 ± 8.2	2. 9 ± 1.7	0.002	0.606	0.002	0.001
< 6 h	56 (16.9%)	12 (11.1%)	14 (13.0%)	30 (25.9%)	0.005	0.676	0.005	0.015
6–12 h	29 (8.7%)	16 (14.8%)	9 (8.3%)	4 (3.4%)	0.010	0.137	0.003	0.118
12–24 h	18 (5.4%)	11(10.1%)	7 (6.5%)	0	0.003	0.325	< 0.001	0.005
> 24 h	27 (8.1%)	17 (15.7%)	10 (9.3%)	0	< 0.001	0.150	< 0.001	0.002

Data are presented as number of patients (percentage) or mean ± standard deviation
PONV, postoperative nausea and vomiting
*Uncorrected p values (for the three-way comparison)
^†Bonferroni-corrected p values: p1, Group A vs. B; p2, Group A vs. C; p3, Group B vs. C. The corrected significance threshold was 0.016

ISSN: 2050-6511