Comparison of three different prophylactic treatments for postoperative nausea and vomiting after total joint arthroplasty under general anesthesia: a randomized clinical trial

Table 5 Requirement of rescue treatment for PONV and pain during the postoperative 48 h

	Group A (n = 108)	Group B (n = 108)	Group C (n = 116)	p*	p1^†	p2^†	p3^†
Metoclopramide (mg)	6.5 ± 1.1	2.9 ± 1.2	1.4 ± 0.5	0.047	0.055	0.017	0.415
Ondansetron (mg)	1.7 ± 0.5	1.7 ± 0.5	0.6 ± 0.1	0.238	-	-	-
Oxycodone (mg)	33.2 ± 8.7	17.9 ± 9.7	1.8 ± 0.3	< 0.001	0.001	< 0.001	< 0.001
Pethidine (mg)	20.4 ± 8.3	20.6 ± 9.8	6.0 ± 1.0	0.002	0.959	0.005	0.001

Data are presented as mean ± standard deviation
PONV, postoperative nausea and vomiting
*p values with one-way analysis of variance; ^†p values with Tukey’s post hoc test
P1, Group A vs. B; p2, Group A vs. C; p3, Group B vs. C

ISSN: 2050-6511