Fig. 4
From: New tricks for old drugs- praziquantel ameliorates bleomycin-induced pulmonary fibrosis in mice
PZQ suppresses the activity of fibroblast in vitro. (A) OD of mouse lung fibroblasts treated with TGF-β (0, 0.1, 1, 10, 20, 50 ng/ml) measuring by MTT. (B) OD of mouse lung fibroblasts treated with PZQ (0, 0.05, 1, 4, 8, 16, 32 μg/ml) measuring by MTT. (C) OD of mouse lung fibroblasts treated with TGF-β (0, 10 ng/ml) and PZQ (0, 0.01, 0.1, 1, 10 μg/ml) for 48 h measuring by CCK-8. #compared with cells treated without TGF-β or PZQ; *compared with cells only treated with TGF-β. These experiments were repeated three times. All quantification graphs represent mean ± SEM. ##P < 0.01. *P < 0.05. **P < 0.01