Fig. 3From: Drug-drug interaction assessment based on a large-scale spontaneous reporting system for hepato- and renal-toxicity, and thrombocytopenia with concomitant low-dose methotrexate and analgesics useDrug-drug interaction signal analysis based on the number of reported cases of rheumatoid arthritis (RA) patients assigned to 4 × 2 contingency tables. The four drug-drug interaction algorithms were described in the materials and method section. MTX: methotrexate; ADE: adverse drug eventsBack to article page