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Table 1 Characteristics of the included studies in meta-analysis

From: The effect of oral supplementation of Paricalcitol on C-reactive protein levels in chronic kidney disease patients: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials

studies

Country

Study Design

Participant

Sample size and Sex

Sample size

Intervention Duration

(Week)

Means Age

Means BMI

Intervention

IG

CG

IG

CG

IG

CG

Paricalcitol

dose (µg/d)

Control group

Alborzi et al. 2008(a)

USA

Parallel,

R, PC, DB

patients with Chronic Kidney Disease

16

F:14

M:2

8

8

4

72.6 ± 9.1

68.4 ± 12.4

34.3 ± 9.1

35.4 ± 7.7

1

Placebo

Alborzi et al. 2008(b)

USA

Parallel,

R, PC, DB

patients with Chronic Kidney Disease

16

F:14

M:2

8

8

4

67.5 ± 9.1

68.4 ± 12.4

35.0 ± 6.5

35.4 ± 7.7

2

Placebo

Lundwall et al. 2015(a)

Sweden

paralell,

R, PC, DB

patients with Non-Diabetic Chronic Kidney Disease

24

F:4

M:20

12

12

12

66.1 ± 7.9

59.1 ± 11.6

26.4 ± 3.5

26.8 ± 2.8

1

Placebo

Lundwall et al. 2015(b)

Sweden

paralell,

R, PC, DB

patients with Non-Diabetic Chronic Kidney Disease

24

F:NR

M:NR

12

12

12

70.8 ± 10.0

59.1 ± 11.6

28.1 ± 2.4

26.8 ± 2.8

2

Placebo

Thethi et al. 2015

USA

paralell,

R, PC, DB

patients with type 2 diabetes and chronic kidney disease

46

F:NR

M:NR

23

23

12

64 ± 4.5

61 ± 5

NR

NR

1

Placebo

Zoccali et al. 2014

Italy

paralell,

R, PC, DB

patients with Chronic Kidney Disease

88

F:31

M:57

44

44

12

63 ± 11

62 ± 12

29 ± 5

29 ± 5

2

Placebo

  1. Abbreviations IG, intervention group; CG, control group; DB, double-blinded; SB, single-blinded; PC, placebo-controlled; CO, controlled; RA, randomized; NR, not reported; F, Female; M, Male; NR, not reported