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Table 4 Permeation kinetic parameters of Huperzine A in ethosomes gel, ordinary gel, and cream (n = 3)

From: Preparation and evaluation of transdermal permeation of Huperzine A ethosomes gel in vitro

Formulation

Q-t equation

R2

Q24/μg · cm−2

J/μg · cm−2 · h−1

Qs/μg · cm−2

Ethosomes gel

Q = 1.802 t + 2.541

0.9474

40.992 ± 4.826

1.802

10.159 ± 1.213

Ordinary gel

Q = 0.9968 t + 2.230

0.8584

21.490 ± 1.988

0.9968

4.856 ± 0.356

Cream

Q = 0.8005 t + 1.056

0.8787

16.800 ± 1.571

0.8005

3.089 ± 0.153