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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: Immuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessment

Fig. 1

Initial evaluation of standard anticancer drugs. (a) The 384-well plate-based tumor-immune model system with mono- and co-cultures analyzed using an image-based readout. (b-c) The viability (expressed as % of control) in HCT116-GFP (b) and A549-NLR (c) monocultures and cancer-immune co-cultures after treatment with the drug panel at 1 µM and 10 µM for 72 h (data shown as means from three technical replicates). (d-e) Bliss scores calculated at 1 µM and 10 µM for the 16 drugs that were selected for validation experiments

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